The website reports that the 34-year-old singer, suffered a second seizure at the hospital, and his representative confirmed to the site that he had suffered multiple seizures.
Four years ago, Lil Wayne, born Dwayne Michael Carter Jr, spent several days at a Los Angeles hospital, after which he told radio station Power 106 he was epileptic and prone to seizures.
Lil Wayne was booked to perform in Las Vegas late on Sunday night.
Born in New Orleans, he started his professional career at the age of nine.